Challenges and Strategies

The Global CEO Initiative on Alzheimer's Disease recognizes that now is an unprecedented time in the national and global fight to address the enormous challenges posed by Alzheimer's disease. Governments around the world have recognized the magnitude of the problem – including its crippling present and future health, fiscal, social and economic impacts – and have begun to take meaningful actions to address them. These actions have identified Alzheimer's and dementia as a paramount health priority, have produced comprehensive national and regional plans to attack this problem and have committed increased public resources to support research and therapy development, care improvement, and caregiver support initiatives.
The impediments standing in the way of breakthroughs in diagnosis, treatment and care are many:

  • There is no clear and prioritized Alzheimer’s research agenda.
  • The Alzheimer’s therapy development process is long, costly and risky. If this does not change, it will be increasingly unlikely to attract the levels of investment needed to deliver effective Alzheimer’s treatments in the coming years.
  • Today’s financing mechanisms and incentives – both public and private – lack the innovative approaches needed to share the risks of early phase therapy development or to support the development of cost-saving care interventions.
  • Alzheimer’s remains highly stigmatized and its diagnosis widely feared, chilling efforts to spur early detection, diagnosis and intervention and discouraging patients from becoming critically needed partners in clinical research.

The members of the CEO Initiative understand these challenges and are committed to marshaling the energy, resources, and expertise required to prevent and effectively treat Alzheimer's disease by 2025 and to improve the lives of all those affected by the disease. Together, members will apply fundamental business skills of goal-setting, planning and evaluation to this immense effort and embraces the invitation extended by governments to form the robust public-private partnerships necessary to achieve these shared goals.